Charles S. Holladay, MD, FACP

Medical Oncology and Hematology Specialist
A South Carolina native, Dr. Holladay joined Charleston Oncology in 2001. He is a graduate of the Medical University of South Carolina where he also completed his residency and fellowship. Dr. Holladay received his undergraduate degree from Francis Marion College in Florence, South Carolina, and completed a master’s degree in science from the University of South Carolina. He is board-certified in internal medicine, hematology, and medical oncology.

Stories From Dr. Holladay’s Patients

Gabriel Middlebrook, Lymphoma

Patient Gabriel (Gabe) Middlebrook, a former Charleston Southern University football player, was recently diagnosed with Hodgkin’s Lymphoma. He is being treated by Dr. Charles Holladay at Charleston Oncology’s North Charleston office. Gabriel’s journey is especially close to our Charleston Oncology team, as he is the twin brother of Chelsea Middlebrook, former Operations Manager at our Tricom location.

Marie Metts

It has been eight years since we started our journey together. From our first meeting, I knew I was going to be in good hands. Dr. Holladay took the time to show and explain to me what my treatment and plan of attack would be for my breast cancer. Dr. Holladay took time to explain how long it would take and all the side effects of chemo and what could be done to help offset or soften the side effects. There were no surprises and Dr. Holladay and his entire TEAM made it as enjoyable of a fight it could be with supporting me and my family during that time. Having Dr. Holladay and his team on my side to fight my cancer was a pleasure. I appreciate Dr. Holladay and would vote for him to be Man of the Year, he is, in my opinion, truly the BEST doctor and I thank him for helping me during a difficult time. God Bless Dr. Holladay—and Thank You!

Choose your preferred location

West Ashley

North Charleston



Mt. Pleasant


Send UsA Message

    A Grateful Patient’s Breast Cancer Journey

    A Grateful Patient’s Breast Cancer Journey

    I am currently undergoing treatment for breast cancer at Roper St. Francis Hospital and would like to acknowledge two physicians who truly embody your mission of “healing with compassion, faith and excellence”.

    read more
    National Cancer Survivor Month

    National Cancer Survivor Month

    Please join Charleston Oncology and the American Association for Cancer Research (AACR) in support of National Survivor Month, celebrating those who have fought the disease and those currently in treatment.

    read more
    Call Now Button