Charles S. Holladay, MD, FACP

Medical Oncology and Hematology Specialist

A South Carolina native, Dr. Holladay joined Charleston Oncology in 2001. He is a graduate of the Medical University of South Carolina where he also completed his residency and fellowship. Dr. Holladay received his undergraduate degree from Francis Marion College in Florence, South Carolina, and completed a master’s degree in science from the University of South Carolina. He is board-certified in internal medicine, hematology, and medical oncology.

Stories From Dr. Holladay’s Patients

Gabriel Middlebrook, Lymphoma

Patient Gabriel (Gabe) Middlebrook, a former Charleston Southern University football player, was recently diagnosed with Hodgkin’s Lymphoma. He is being treated by Dr. Charles Holladay at Charleston Oncology’s North Charleston office. Gabriel’s journey is especially close to our Charleston Oncology team, as he is the twin brother of Chelsea Middlebrook, former Operations Manager at our Tricom location.

Marie Metts

It has been eight years since we started our journey together. From our first meeting, I knew I was going to be in good hands. Dr. Holladay took the time to show and explain to me what my treatment and plan of attack would be for my breast cancer. Dr. Holladay took time to explain how long it would take and all the side effects of chemo and what could be done to help offset or soften the side effects. There were no surprises and Dr. Holladay and his entire TEAM made it as enjoyable of a fight it could be with supporting me and my family during that time. Having Dr. Holladay and his team on my side to fight my cancer was a pleasure. I appreciate Dr. Holladay and would vote for him to be Man of the Year, he is, in my opinion, truly the BEST doctor and I thank him for helping me during a difficult time. God Bless Dr. Holladay—and Thank You!

Choose your preferred location

West Ashley

North Charleston

Downtown

Summerville

Mt. Pleasant

Walterboro

Send UsA Message

LOCATION*

PROVIDER*

FIRST NAME*

LAST NAME*

EMAIL ADDRESS*

PHONE*

Birthdate*

MESSAGE

I understand and agree that any information submitted will be forwarded to our office by email and not via a secure messaging system. This form should not be used to transmit private health information, and we disclaim all warranties with respect to the privacy and confidentiality of any information submitted through this form.*

Living In Full Bloom

May 22, 2025

From diagnosis to treatment and follow-ups, Charleston Oncology, as a part of the Department of Bon Secours St. Francis’ leading multidisciplinary cancer care team, plays a vital role in guiding patients through their breast cancer journey.

Detecting and Treating Head and Neck Cancers

Apr 24, 2025

From diagnosis to treatment and follow-ups, Charleston Oncology, as a part of the Department of Bon Secours St. Francis’ leading multidisciplinary cancer care team, plays a vital role in guiding patients through their breast cancer journey.

The Power of a United Breast Cancer Team: Your Leading Breast Cancer Allies

Oct 1, 2024

From diagnosis to treatment and follow-ups, Charleston Oncology, as a part of the Department of Bon Secours St. Francis’ leading multidisciplinary cancer care team, plays a vital role in guiding patients through their breast cancer journey.

Celebrating Strength and Hope: Join Us for the 6th Annual Pink Promenade

Jun 19, 2024

Celebrating Strength and Hope: Join Us for the 6th Annual Pink Promenade Mount Pleasant Towne Centre is thrilled to announce our 6th Annual Pink Promenade Breast Cancer Awareness Fundraiser, an event that embodies hope, strength, and resilience. Scheduled for...

Jenny’s Journey Reflects Our Mission

Apr 30, 2024

At Charleston Oncology, the mission of healing all people with compassion, faith and excellence resonates through the hallways and translates into every patient interaction.

Myra Walks in a Patient’s Shoes

Apr 8, 2024

In the busy corridors of Charleston Oncology on a triple-booked day of patients, a moment of pure human kindness unfolded, illustrating what it truly means to walk in a patient’s shoes.

« Older Entries